Medical Innovation's High Price

Matthew Herper, 07.25.2003, 12:00 PM ET

NEW YORK - Medical innovation doesn't come cheap.

Below is a list of the most expensive prescription medicines available from drugstore.com (nasdaq: DSCM - news - people ), the online pharmaceutical retailer, at yesterday's prices. Because drugstore.com negotiates discounts and competes with other retailers on price, these figures will not remain static. Already, they factor in some level of discount. And plenty of expensive remedies are not included in this list. Many cancer drugs, in particular, are sold directly to hospitals and specialists because they must be injected intravenously. These are medicines that consumers can actually buy. And listed below are costs a consumer without any health insurance would pay.

To look at this snapshot of pharmaceutical costs is to view a scorecard of the biotechnology industry's biggest innovations. Most of these drugs, listed at various dosages, are proteins made using recombinant DNA technology. They mimic--or exactly duplicate--proteins that are missing in the bodies of patients. Johnson & Johnson's (nyse: JNJ - news - people ) Procrit and Amgen's (nasdaq: AMGN - news - people ) Aranesp spur the body to make oxygen-carrying red blood cells, warding off anemia. Amgen's Neupogen and Neulasta pull a similar trick with white blood cells, which help the body ward off infection. During chemotherapy, white blood cells can become depleted. Eli Lilly's (nyse: LLY - news - people ) Humatrope and Serono's (nyse: SRA - news - people ) Serostim are growth hormones that can be used to help adults and children whose bodies aren't making enough. These drugs represent the cornerstone on which the biotechnology industry had been built over the past 25 years. But discovering them was expensive, and making them is much more complicated than making a conventional pill like aspirin.

Also present are Novartis' (nyse: NVS - news - people ) Gleevec and AstraZeneca's (nyse: AZN - news - people ) Iressa, two of the first cancer drugs to work by deliberately targeting specific genes or proteins. The genomics revolution, if it happens, will not be cheap. One more reason medical costs, particularly drug costs, are likely to keep expanding.

The Most Expensive Medicines At Drugstore.com

These are the priciest prescription drugs at the popular online pharmacy. Prices are subject to fluctuation due to negotiation, and all are somewhat discounted.
Rank
Drug Name
Drugmaker
Use
Strength
Quantity
Price
1
Neupogen Amgen (nasdaq: AMGN - news - people ) Stimulates the production of white blood cells to help prevent infections related to chemotherapy. 480 mcg/ml 1.6 ml vial
$2,800
2
Neulasta Amgen Longer-lasting form of Neupogen; shots are given less often. 6 mg/0.6 ml solution 0.6 ml syringe
2,599
3
Aranesp Amgen Treats anemia by stimulating red blood cells. 150 mcg/0.75 ml solution Four vials
2,556
4
Tobi Chiron (nasdaq: CHIR - news - people ) Nebulized antibiotic used to treat bacterial infections in cystic fibrosis 300 mg/5 ml solution 112 ampules
2,530
5
Lupron Depot TAP Pharmaceuticals, a joint venture of Takeda and Abbott (nyse: ABT - news - people ) Shuts down testosterone to prevent the spread of prostate cancer. Also used to treat endometriosis and central precocious puberty. 30 mg One box kit
2,300
6
Humatrope Eli Lilly (nyse: LLY - news - people ) Human growth hormone. Improves growth in children, treats adults with problems of the pituitary gland. 24 mg Two cartridges
2,200
7
Gleevec Novartis (nyse: NVS - news - people ) Targeted cancer pill used to treat chronic myelogenous leukemia and gastrointestinal stomach tumors (GIST). 400 mg 30 tablets
2,140
8
Procrit Johnson & Johnson (nyse: JNJ - news - people ) Used to treat anemia in cancer, HIV, kidney disease and following surgery. 40000 u/ml 1 ml vial Four vials
1,858
9
Neupogen Amgen Stimulates the production of white blood cells to help prevent infections related to chemotherapy. 300 mcg/ml Ten vials
1,756
10
Lupron Depot TAP Pharmaceuticals, a joint venture of Takeda and Abbott Shuts down testosterone to prevent the spread of prostate cancer. Also used to treat endometriosis and central precocious puberty. 22.5 mg kit One kit
1,735
11
Iressa AstraZeneca (nyse: AZN - news - people ) Used alone to treat lung cancer after other medicines fail. 250 mg 30 tablets
1,709
12
Aranesp Amgen Treats anemia by stimulating the growth of red blood cells. 100 mcg/0.75 ml solution Four vials
1,700
13
Temodar Schering-Plough (nyse: SGP - news - people ) Used to treat adults with certain brain tumors that have recurred or progressed. 250 mg Five capsules
1,700
14
Humatrope Eli Lilly Human growth hormone. Improves growth in children, treats adults with problems of the pituitary gland. 12 mg solution Three cartridges
1,634
15
Sandostatin Novartis Used to treat severe diarrhea caused by cancer and to suppress growth hormone. 0.5 mg/ml 20 ml
1,586
16
Valcyte Roche Treats severe retinitis that occurs during AIDS infection. 450 mg 60 tablets
1,530
17
Serostim Serono (nyse: SRA - news - people ) Used to improve growth in children. Also treats wasting diseases like those that occur with AIDS. 6 mg solution Seven vials
1,500
18
Lupron Depot TAP Pharmaceuticals, a joint venture of Takeda and Abbott Shuts down testosterone to prevent the spread of prostate cancer. Also used to treat endometriosis and central precocious puberty. 11.25 mg kit One box kit
1,440
19
Procrit Johnson & Johnson Used to treat anemia in cancer, HIV, kidney disease, and following surgery. 20000 u/ml 1 ml vial Six vials
1,400
20
Humatrope Eli Lilly Human growth hormone. Improves growth in children, treats adults with problems of the pituitary gland. 6 mg solution Five cartridges
1,376

Source: drugstore.com, Forbes reporting. Drug prices as of July 24, 2003.